ImmunotiX 500^™ delivers 500 mg of whole glucan particle per capsule, providing beta 1,3/1,6 glucan—that's double the dose of ImmunotiX 250^™. Beta 1,3/1,6 glucan is a unique complex carbohydrate purified from Saccharomyces cerevisiae (baker’s yeast). It is natural, non-genetically modified (non-GMO), hypoallergenic, patented, and generally recognized as safe (GRAS). Taken orally, ImmunotiX 500 primes and mobilizes the cells that support the body's first-line immune response.*

For ongoing immune support: Take one capsule daily, first thing in the morning or last thing at night (before or well after a meal), with a full 8 oz glass of water. For fast-acting immune support: Take up to two capsules per day, as above; or use as directed by your healthcare practitioner.*

Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner. Do not use if tamper seal is damaged.

Storage: Keep closed in a cool, dry place out of reach of children.

Does Not Contain: Wheat, gluten, corn, yeast protein, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

veness. Mannan, a potential trigger of allergic reactions or bowel exacerbation, has been removed. ImmunotiX 250™provides 250 mg beta-glucan per capsule, while ImmunotiX 500™ provides 500 mg beta-glucan per capsule.* Ongoing research has unveiled a detailed mechanism of action, including activation of macrophages, neutrophils, and T-cell–mediated immunity.[3,8,9] Orally administered yeast beta-glucan is processed by macrophages—the first line of defense in cellular immunity[8]—with subsequent increases in phagocytosis, selective cytokine release, and oxidative degranulation.[10] Macrophages degrade beta-glucan into small fragments that are then bound to neutrophils (granulocytes), the most abundant immune cells in the body. Neutrophils then become primed and are better able to provide support against microbial challenges.[4] Through a process called chemotaxis, these primed neutrophils migrate to target sites with enhanced immune actions.[3, 11] Prophylactic administration of beta-glucan was found to positively affect levels of the antioxidant enzymes catalase and superoxide dismutase, moderate tissue-damaging cytokines, and assist in ameliorating microbial imbalance.*[12] Research demonstrates a sustained release of soluble fragments over a multi-day period, providing a unique mechanism of action for the beta-glucan form found in ImmunotiX. Studies also indicate that the entrance of these soluble fragments into the bone marrow may affect white-blood–cell recovery, further enhancing its health effects.[13] Individuals at increased risk for immune challenges, those in need of immune support, or those undergoing surgery have been found to benefit from ImmunotiX.[2,6,8,12,14] A 12-week, randomized, phase II, double-blind, placebo controlled, parallel-group trial of 1,3/1,6 beta-glucan from S cerevisiae was conducted. Long-term use of betaglucan was well tolerated and resulted in a reduction